Can Dosing with Psilocybin Mushrooms Treat Depression?

I found the benefits of psychedelics to be kinda short lasting, tbh. The perspective shifts were profound at the time, but wore off fairly quickly. In contrast, I found the benefits of intense meditation (Vipassana) to be MUCH longer lasting. It's been over 10 years since I practiced Vipassana regularly, but the techniques and perspectives I developed from learning it are still very helpful today. They've helped a lot with mental wellbeing over the years

Definitely needs more research. Seems to me the studies mentioned here are approaching Psilocybin as a chemical treatment for a chemical disorder. That strikes me as almost certain to get poor results. Whether we're talking depression, anxiety, CPTSD or PTSD, other work through a therapist would be important. Psilocybin is not likely to correct a mental health problem chemically but it could have significant results in conjunction with other kinds of cognitive therapies. Psilocybin may provide some temporary chemical modifications to the brain that eases suffering but you'd expect the effects to be temporary. Psilocybin could open the door to better mental health but it can't walk you through it.

highly recommend michael pollan's book "how to change your mind" to anyone who wants to know more! there is much much more to know about this topic and pollan does an incredible job.

I wonder if there is good research on adaptogenic mushrooms and herbs, these are legal and likely easier to get approval for Research studies e.g. reishi, chaga, lions Mmane, cordyceps

Absolutely love Healthcare triage. About as non-biased as you can get and he looks at tons of different studies so you don't have to.

The trial that has no significance mentioned at 4:02 was testing for difference between psicobylin 25 mg alone in two doses vs psicobylin 1 mg in two doses with escitalopram in between. No significance doesn’t mean the drug didn’t work, it may just have meant that the dosage is still no determined. I’m unsure why they added the escotalopram on the other group though as it would’ve been better to have it as a third separate group for control, although that would’ve been a phase 3 trial 🤔

I weigh 280Lbs or 127Kg, I took 2.7 grams of Psilocybin Cubensis and had a 3 hr strong introspective experience. Afterwards I can say that my Suicidal Ideation is no longer a symptom I live with 🙂 , This is not the result of some single moment during my experience but is just something I noticed about myself. Depression down 50% Anxiety raised 30%. Although my experience mildly increased my anxiety I believe this to be a symptom of something disturbing I realized about myself that I wrestled with during the come down. I think I’m eventually going back to veganism which I abandoned last month because I was somewhat homeless but had access to fast food through EBT. I would rate Psilocybin as a 8/10. It helped and I’m a healthier person.

Speaking of virus, this episode reeks of drug war propaganda. Get over it. The people won the drug war. The only thing the drug war did was made drugs more available less expensive and more potent.

It's becoming fairly clear, little by little, that psilocybin can be used to treat depression at least in some people. It's just not clear yet how well, how lasting the effects, how safely (for the wide array of patients with depression and co-morbid mental illnesses.)

We should have known this fifty years earlier. Thanks to Nixon's drug laws, we couldn't. How many people suffered from severe depression or are gone because of suicide as a result of his shallow thinking?

That's strange that's considered a high dose when street use 3.5 grams is standard dose

A classmate of my in my Psych masters was doing this for her thesis. She sadly didn't find anything in her study, but she really hopes it can help ^€^

Great video info, love the content. Hope topics like this will be more discussed. Psychedelics are great..!

Guys long story short it works I’m living proof

I pray that you will find true peace in Jesus. Here is a story from my best friend that I would like to share with you. God bless you.

Precious Memories-By Sonya Lakey

Family Story
Little did our family of six know that Friday evening, September 24th, 2021, would be the last night our family would be complete. We laughed together, played games, sang, and enjoyed listening as our 16-year-old son, Ethan, played the piano for us. I packed a lunch for Ethan for a church mountain hike he was going on the following day.
My mother (who was visiting from out of state) and I woke early with Ethan on Saturday morning. He hugged me and smiled, never pulling away or rushing me. He got in the car, waved, said he'd see me later and he loved me. It was hard to watch my "new driver" heading out on his own that morning. As Ethan pulled out of the gate, I turned to my mother and said, "It's just so hard letting go." Little did I know how much "letting go" I was really doing. That was the last time I saw Ethan. He did not make it home that evening.

That afternoon, a friend tried to contact my husband, leaving an urgent message to call him back. He tried several times to return the call to no avail. As we were preparing supper, an overwhelming feeling of deep concern for Ethan filled my heart. I quietly blinked back tears. I glanced out the window, half expecting to see a police officer pull up to the house, but no one arrived. However, within a few minutes, a patrol car DID pull into the driveway. In my heart, I feared the worst. My husband and I went out to meet the officer, who confirmed our fears. Hesitantly, he told us our son had fallen off of
a bluff and had succumbed to his injuries. Our hearts were crushed; they still are.

Yet, in all of our brokenness, deep, continual grief and loneliness, our family has such a blessed Hope and assurance that we will see our dear son and brother again. You see, when Ethan was a young boy, he was saved; he put his faith in Jesus alone to forgive his sins and to take him to Heaven when he died. He realized some very important truths from the Bible that he would want to share with you.

His Story

Everyone is a sinner. Sin is any violation of God’s Law. God is holy, just and righteous, and He cannot allow sin in His presence. Ethan realized that he – like all of us – had sinned; and his sin separated Him from God.
“For all have sinned, and come short of the glory of God; ” (Romans 3:23)
“Wherefore, as by one man sin entered into the world, and death by sin; and so death passed upon all men, for that all have sinned:” (Romans 5:12)

He understood that, because of his sin, he deserved to spend eternity in Hell.
“For the wages of sin is death;” (Romans 6:23a) [Wages: price]

“But the fearful, and unbelieving, and the abominable, and murderers, and whoremongers, and sorcerers, and idolaters, and all liars, shall have their part in the lake which burneth with fire and brimstone: which is the second death.” (Revelation 21:8)
Ethan believed that Jesus, God’s Son, paid the price for all sin when He died on the cross – because His sinless sacrifice was the only thing that could satisfy the just demands of a righteous, holy God. Jesus was buried in a borrowed tomb, but He arose the third day, triumphant over sin, death, and Hell. Jesus is alive today!

“For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life.” (John 3:16)
“For by grace are ye saved through faith; and that not of yourselves: it is the gift of God: Not of works, lest any man should boast.” (Ephesians 2:8-9)
Ethan was sorry for his sin, repented (turned), and received by faith the free gift that God offered to him.
“For whosoever shall call upon the name of the Lord shall be saved.” (Romans 10:13)
“…but the gift of God is eternal life through Jesus Christ our Lord.” (Romans 6:23b)
Because of this great salvation, Ethan lived his life serving Jesus. He worked hard to spread this Good News to the world. He is alive in Heaven with Jesus today; and because of this great HOPE in Christ, we know we will see him again soon – not because he was a great kid, but because of his faith in the great Saviour!

“And I give unto them eternal life; and they shall never perish, neither shall any man pluck them out of my hand.” (John 10:28)

Your Story
What about you? What if you had fallen to your death that day – What if you were to die today? Where will you spend eternity – Heaven or the Lake of Fire? There will not be any parties in the Lake of Fire. It is a place of eternal torment for those who reject God's Son.
The Word of God is very clear that there is only One Way to Heaven.
“Jesus saith unto him, I am the way, the truth, and the life: no man cometh unto the Father, but by me.” (John 14:6)

We did not know that Ethan would step into eternity that day; however, because he put his faith in Jesus alone for his salvation, Ethan was ready to go. Some day – perhaps today – you will take your last breath here on earth, and you will step into eternity. Where you spend eternity is determined by what you do with Jesus Christ. Will you accept Him or reject Him? You are not promised another day or another breath. Eternity begins soon – Are you ready?
“…Believe on the Lord Jesus Christ, and thou shalt be saved…” (Acts 16:31b)

“For whosoever shall call upon the name of the Lord shall be saved.” (Romans 10:13)
“(…behold, now is the day of salvation.)” (2 Corinthians 6:2c)
*******************************************************
If you need more help or if you would like to send a word of encouragement to the family, please go to:
https://www.facebook.com/GITM-Foundation-113997824650357/

If you don't have a church to attend, we would love for you to join us in person @ Liberty Faith Bible Church in Norwood, Mo. every Sunday morning central time 11:00 A.M., Sunday evening 7:00 P.M., and Wednesday evening 7:00. P.M. where you will hear sound, biblical preaching from God's Word as well as uplifting, godly music.

Or you can join our livestream family at:

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I am feeling the same way also I put too much on my plate and it definitely affect my stress and anxiety levels.

what a shocker, the "science" says that big-pharma SSRI/SNRIs are better. you pronounced escitalopram wrong also.

Microdosing psiIocybin mushroom 🍄 has put depression, insomnia, PTSD,ADHD and anxiety into remission. Psilocybin mushrooms, commonIy known as magic mushrooms, are a poIyphyletic informal group of fungi that contain psilocybin which turns into psilocin upon ingestion. Biological genera containing psiIocybin mushrooms include CopeIandia, Gymnopilus, lnocybe, PanaeoIus, PhoIiotina, Pluteus, and Psilocybe.

Anecdotal I suppose, but, my partner was severely depressed and suicidal and psilocybin treatment at a clinic saved his life and gave him a positive outlook on life

Psychedelic are just an exceptional mental health breakthrough. It is quite fascinating how effective they’re against depression and anxiety.