Essentials: Understanding & Treating Addiction | Dr. Anna Lembke

In this Huberman Lab Essentials episode, my guest is Dr. Anna Lembke, MD, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic at Stanford University School of Medicine.

We discuss how dopamine drives reward, motivation and addictive behaviors. Dr. Lembke explains the concept of the pleasure-pain balance of dopamine and how this cycle plays a key role in the development and persistence of addiction. We also discuss some of the challenges of addiction recovery, including withdrawal, relapses and the potential benefits of psychedelic-assisted therapy.

Episode show notes: https://go.hubermanlab.com/xbtub2m

Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/p3JLaF_4Tz8

Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S

*Follow Huberman Lab*
Instagram: https://www.instagram.com/hubermanlab
Threads: https://www.threads.net/@hubermanlab
X: https://twitter.com/hubermanlab
Facebook: https://www.facebook.com/hubermanlab
TikTok: https://www.tiktok.com/@hubermanlab
LinkedIn: https://www.linkedin.com/in/andrew-huberman
Website: https://www.hubermanlab.com
Newsletter: https://www.hubermanlab.com/newsletter

*Dr. Anna Lembke*
Website: https://www.annalembke.com

*Timestamps*
00:00:00 Anna Lembke
00:00:15 Dopamine, Reward & Movement
00:01:54 Baseline Dopamine; Genetics, Temperament & Addiction
00:05:24 Addiction, Modern Life & Boredom
00:07:18 Pleasure-Pain Balance, Dopamine, Addiction
00:12:39 Resetting Dopamine, Substance or Behavior Recovery, Tool: 30-Day Abstinence
00:14:26 Relapse, Addiction, Reflexive Behavior, Empathy
00:18:39 Triggers, Relapse, Dopamine
00:21:37 Shame, Truth Telling & Recovery
00:23:58 Addiction, Psychedelic-Assisted Therapy, Psilocybin, MDMA
00:29:01 Social Media & Addiction, Tool: Intentionality

Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

46 Comments

  1. Thank you for watching! If you enjoyed this topic and episode, please click the “Like” button and subscribe to our channel on YouTube. Thank you for your interest in science! — Andrew

  2. For those from day 1 to 10, I found walking and hitting the gym will ease the uncomfortable feelings, but you must endure through that period of desire

  3. how you really overcome addiction, is by healing the trauma inside of you. Because you can get clean all you want and that's just the very first step, but if you do not heal inside of you what is broken, you will not only substitute it for something else even if it's legal, but you will return even if your two decades clean at some point you will return.

  4. HOLY CRAP. Finally someone who sees the world as I do. Im a recovering addict. Clean for almost 3 years now. I wasn't trying to cover up any trauma, I wasn't depressed, I was bored and I had a few head injuries and I think it made me more impulsive than most, also have addiction in my family but I am only addict of my siblings. I always told the health care workers that I was just bored and had discovered pain pills when I had a surgery when I Was 16 and it was the best feeling ever and I was constantly chasing that feeling. People aren't lying when they say those drugs are 1000x better than sex, especially for males. Sex for males really isn't anything great.

    The way I have stayed clean is by being as active as possible. Working out like my life depends on it, I work out daily. I practice meditation and this was a big one because like I said, I was constantly bored. Learning how to sit with yourself and your thoughts and feelings is such a great tool to have. I want to write a book and write music, and constantly learn. Part of me thought that I should get a job that's something human's have done forever like be a builder, or work on an oil rig, do something physically and mentally challenging , but I did this in my early 20s and it's another reason why I was using drugs. I would be outside in 0 degree weather with 25 mph winds for 8 hours a day and I'd get home and just not be able to move. Cover myself in blankets and try to figure out how to feed myself. If I can use my brain to make money, I would much rather do that. I am staying in shape physically though just so that if I ever do need to do physical labor again, I will be able to. Praying that retard of a president doesn't really fuck everything up.

    But basically, I shifted my perspective. I gained this insight about hard work and effort that I never had had before. Once I got a taste of the rewards of hard work, I realized it's what I was missing. I want to learn how everything works, I want to learn how to be good with money, I want to learn how to sail, I learned how to skateboard. This is what we have to do in today's world. You don't need survival skills anymore, so instead of thinking that's a bad thing because we are bored, you take advantage of that fact and develop all these skills and knowledge and pass them on.

  5. Dr. Lembke's comment about humans being bored is so spot on. I just realized how much this explains the prevalence of ADHD now. I see the ADHD boards and all these people realizing when they are in their 30s that they have ADHD and they get adderall (meth), and they are AMAZED at the difference. "Oh my god, I can't believe I sufffered through life without my wonderful medication." You should just say "Wow, meth is awesome, I understand why people like it. I basically use meth, I just get mine prescribed and take it as directed".

    But people are just bored, this is why they have ADHD. Think about it… You have an office job, you are in recruiting, you get to work, you go on the computer, you look at resumes, you call people, you have meetings, you take lunch, you have more meetings, you scroll the internet, you go home. WHO in their right mind could find that interesting? Of course it's going to suck and be hard to do that work because it's fucking pointless. If you were taking care of kids while the husband was out hunting, you wouldn't have adhd.

    Im an addict and I probably have severe ADHD, but I am not going to live cranked out on meth forever and be reliant on that. I am using natural ways to increase focus and motivation and all that good stuff.

  6. I was adicted to heroin dhe devil himsellf
    Translate in Albanien:
    Po nese je i vendost dhe me t,vertet i vendost mundesh me dal nga ferri por pa ec neper të nuk mund të dalësh ju keni pa shum scena mëpar e pranojn OVERDOSE sesa ta lën atë adicti është diqka që smund të pershkruhet as te matet me të ju lutem thuani jo DROGES respekt!🇦🇱🌏

  7. I'm 3 years clean from 12 years of Heroin Addiction. I lost my family, career, health and motivation during that time. I'm trying my best to convince my wife for another chance but ahe doesn't trust me. I was brilliant in my career but now I can't decide what to do and where to move. I'm having difficulty focusing and taking every distraction as an opportunity. I thought quitting and being clean is difficult but now I realized starting a normal life again is more difficult and challenging.

  8. Im in a battle right now. I shouldn't care but I do because something doesn't feel right. I'm not sure I know what the other side is and how much I understand that my pleasures should not be determined with my trauma

  9. I have been a cannabis smoker since the age of 16, I am 26 now, and I have already managed to stop for a few days, even half a week (especially when I am on vacation, and I don't miss it that much because I feel like my brain is discovering a lot of things on vacation and therefore doesn't think about it), however when I am at home, and I stop, currently it has been 4/5 days, but everything seems boring to me, as if I have a drop in motivation, in creativity. I started smoking because I found a form of inner peace in smoking; it soothed my emotions which sometimes overwhelmed me. When I was little, a fit of anger could make me tear down a wall, so I did a lot of sports from the age of 6 to 20, about 4 hours a day. Then, when I started smoking, a kind of calming effect appeared, with a less excessive need to do sports, and an ability to take a strong interest in various subjects to the point of becoming competent in various fields. I have the impression that smoking increases my creativity and curiosity. As for sleep, it's a real ordeal. It's 2 a.m. and I'm wide awake, my head full of thoughts. I feel like cannabis channels my thoughts and allows me to fully immerse myself in various areas, sometimes too much! It's complicated because I'd like to be able to say, "Oh, I'm going to smoke a joint and we'll catch up in three months," but I feel like my impulsive behavior and hyperactivity would bring back my old demons, and I'd go back to the spiral of smoking 24/7. It's really strange. In terms of consumption, around the age of 20, I decided to only smoke "sticks" instead of big joints, and my consumption was like 10 sticks a day, at about 4 grams per week, to give you an idea. Whereas when I was younger I could roll a 1g joint, I felt like I'd found the right compromise. But I realize that it creates stress if I don't have any on hand. Just knowing I have enough to roll a joint reassures me and sometimes even pushes me to challenge myself to quit cannabis. Strangely, it's as if my brain is saying, "You have it available if you ever relapse, but challenge yourself to see how far you can go." But as soon as I decide to quit completely, or even to own any, my brain sees it as a constraint and not a challenge because I know I don't have any and that I'll have to face all kinds of emotions and situations without it. I've known people who were real "vegetables" when they smoked, but that wasn't me. I was alert, active, and motivated to undertake all sorts of things! I tell myself that it depends on the person, and on each person's brain, but I still find many similarities with some comments about their withdrawal.

  10. 4.5 years alcohol free. I’ve been on and off of opiates (kratom oh7 and prescribed pain killers) for 8 years. Once it hooks me all I can do is maintain. Wish I was free from that.

  11. I think the important thing I learned about this is awareness. Awareness is everything, knowing why you're addicted, what your brain is doing, what you're thinking, what and when you get triggers, etc. really helps not only in recovery but also in prevention.

  12. I've been sober and free of illicit drugs for over 21 years, also a qualifide therapist and will help if you need any support to overcome addiction and any other associated trauma

  13. Watching this as the year begins, sets the pace on how to handle the Pain-Pleasure equilibrium. Doing day 8 without alcohol, and the desire is intense, Certainly "You will feel worse before you feel better"

  14. As a Japanese, I was surprised to hear that Anna Renbuke's book, "Dopamine Addiction," describes how earthworms live longer when exposed to moderate temperatures and flies are turned by centrifuges.

    Furthermore, some data show that people who live outside the epicenter and are not exposed to too much radiation have a slightly longer life expectancy and are less likely to develop cancer than those who are not exposed to radiation at all.

    Thank you, America's great psychiatrist

    He translated these books into Japanese and made me pay for them

  15. its always hard for me to start listening to this broadcast but once i hold 5 min it becomes great
    I think learning is really powerful for addiction limitations but it should be in the field the addict likes

  16. Thank you so much

    Please see DrJosefWii-Doerring
    Most mental upset is due to unresolved trauma
    Diet exercise counseling prayer are wonderful healing mechanisms.
    Nobody is missing serotonin. There is a study in theLancet by Dr Joan Moncrieff. With Fox documenting no one is missing serotonin.
    Psychiatric medication, numb mask, and cause many horrific side effects that can be long-term permanent, but also be healed through proper withdrawal.
    Medications can cause addiction physiologically.
    I am praying along with many others that light would be shed on this dark lie over many decades. People can be helped. We’ve lost family members, but will continue to help those we can to understand the truth.

  17. There is a hug difference between pleasure and happiness having pleasure depending of dopamine neurotransmetteur but happiness it's about sérotonine….and just for knowing the only neurotransmetteur that blocked sérotonine production is The Dopaming ….so the people who looking for having just pleasures..fun limits time .they will never feel happy i mean the real happiness ….cause they are on almost of times mad dopamine by their addiction ( behaviour or product ) happiness is a soul spiritual state … pleasure is a body state

  18. Genetics gives you the Gun.. environment gives you the bullets.. Trauma pulls the trigger. Not everyone with genetics will be in addiction, their childhood environment, teen adult environment plays a part and level of lives trauma

  19. After reading “Dopamine Nation”
    I had so much self compassion for myself, and also heart felt empathy for others. What a time to be alive. !
    I’m forever changed, and sober.

  20. Addiction after you reach the bottom and you stay homeless or whatever they do what do you think scares them the most do you think a lot of addiction has a problem with the pressure in the rise of society but what I'm getting at is once they hit that spot they already find they can't have or find no way out of it do you think if there was a a stability within each one of these cities that they would be able to actually control themselves out of it

  21. I don’t have an addiction , but I came here to because something made me want to tell you reading this -You are stronger than you know! You’re gonna get through this! The fact that you’re here reading this means that God wants you to know that THIS TIME you are gonna have victory! That grip is no longer there. You are now healing and heading towards that new life of health, wellness and comfort.
    You may not realize this now, but there is someone that God has plans to place in your path down the road from now. This person is going to be in that same position you were previously in and is going to desperately need YOU (and nobody else) to get them through their struggle. However, GOD won’t be able to fully use you if you don’t take EVERY opportunity to grow into this. HE knows this is going to be a process and will hold onto you through all of this. You just need to put that baggage down and trust HIM through all of this! Because all of this has that purpose of bringing you that wisdom to one day help that person whom HE has waiting down the road. So please, know that you’re not just doing this for yourself. There is someone, later on in life, that is depending on you coming out of this with great wisdom to use in helping them.
    You got this!

  22. I dont even want to quit. It is part of who I am. I relapse daily and don't care. I am not addicted. But it is a sin so i have to quit. When ive had enough but it keeps getting worse. Its too embarrassing to admit.

  23. Extremely few people are able to kick their addictions, maybe 1 in every 1,000 people can.

    This requires levels of willpower that only a tiny percentage of a percentage of people have.