Depression, Anxiety, PTSD: What to Do When Nothing Seems to Work
This video explores what to do when mental health treatments don’t seem effective. Learn how to redefine treatment success, identify key symptoms, and integrate holistic strategies such as nutrition, sleep, and daily activity to improve overall wellness.
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References
Kirsch, I., et al. (2002). “The Emperor’s New Drugs: An Analysis of Antidepressant Medication Data Submitted to the U.S. Food and Drug Administration.” Prevention & Treatment, 5(1).
Turner, E. H., et al. (2008). “Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy.” New England Journal of Medicine, 358(3), 252-260.
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36 Comments
I wish she was my psychiatrist she's better than any I've ever had. 😔
Can hypothyroidism be associated with depression, or the other way around ?
Next summer might be my last time on this earth
Hi Dr. Marks, I was just wondering what your thoughts are on cbd gummies for anxiety and/or insomnia. I have tried them recently but found the amount of time to feel any effects varies widely. Also, I tried melatonin for sleep but I had severe nausea and terrible grogginess the next day. Any advice or thoughts on these would be appreciated. By the way, I love all of your videos and shorts! Big fan here! ❤
27 years old. Diagnosed with PDD (dysthymia) and general anxiety. Been through 8 different antidepressants. Its hard to remember the names, sertraline and bupropion are 2 I do remember. Seen 3 different therapists, and not only did I not find it helpful, It made me more depressed because I'm unable to remember and/or use what they tell me. Its not their fault, they were all great, caring people.
I've also been involuntarily admitted to the psyche ward for being suicidal several times.
I never made it through school, nor have I been able to work without breaking down. Because I can't work and have minimal welfare income, my options have always been extremely limited. It feels like the system is only designed to help people who aren't so crippled by their mental health that they can function enough to afford treatment.
This video doesn't actually provide any insight onto what to do if nothing works, as is the case for me.
I've tried as hard as I could… I can't see an hope on the horizon. I hate myself, I hate feeling this way. Because nothing works at all; death seems the only option. I can't handle having no life, no friends, no value with a horrible depression I can't get rid of.
Any advice for someone in this boat? Doubt it…
this is one of the best channels on mental health ….
Unfortunately therapy hasn't ever helped me in the past decade I've been in it. My meds I guess have helped a little with my outward symptoms, but I still feel depressed. It's hard to accept this is as good as it gets. It makes me want to go off my antidepressants and just drink myself to death instead.
Comment sections like this make me feel less alone. I wish the best of healing to all of us. Thank you all for sharing.
Bhai itni sudh Hindi samaj nahe ati
This is where I’m at now. I take hydroxyzine and Ativan for daily anxiety. I’ve tried so many anti depressants with no success and it worsens my anxiety every time leading me to take my rescue meds. Now my rescue meds don’t work and I sit up all night scared like I am right now. I’m mad at myself and my doctors for letting it get this bad. I made it very clear I did not want to be dependent on a benzo but when you keep thinking well maybe next week I’ll feel better and I can slow down, it never ends. It’s a slippery slope when you have a panic disorder
plese doctor i can not afford the treatement in this hell of country any other types ?natural types
I have been suffering SEVERE depression and anxiety to the point os barely any ADLS being performed last 18 months, i now habe medical problems too as a result. It's 3pm and i still have been too upset to leave my bed. I did finally find distraction through youtube and Dr Marks. Even though I'm 70, I've struggled with this on and off for 11 years since MH forced me to leave work for food.
And yes, doc prescribed benzo diazepam 8 yrs ago and my anxiety kept increasing exponentially each year.
Not only am i suffering all you mention to the MAX, i also am now 70 and the mental health problems, especially the severe ones last 8 yrs now affecting cognitive ability even WORSE as i am also isolated and totally alone with no support or even someone i can turn to advice for in this new housing that has so many problems need fixing ASAP. I am TERRIFIED!! Still i bed at 3.15pm and can't bear to leave messy, cluttered room to face rhe rest of the unit. Mental Health professionals now making me WORSE for last 3 months!! because of incompetence in helping deal with the diazepam. I shouldn't be the one trying to research and teach THEM. It has killed me. I could have been worrking on myself. But they broke me. I am litterally waiting for the end to come through the door and take me. This is not living but at 70, it's impossible to keep going like this. NOTE: It is NOT the age that is causing what Dr Marks is talking about as this has been going off and on for many years, each time i fell into the black hole thanks to "loved ones" now gone from my life (but the trauma still remains). THIS time, the ADLS, and all the other severe things mentioned in this video are not going to leave. I can feel old age adding to it now, especially ISOLATED old age. I don't have a chance now. Too tired, too old and we all know how it takes YEARS to rewire the brain. I don't have months let alone years, nor the physical strength of youth. Even 15 yrs younger now "might" have helped. The ONLY thing that can SAVE me now is to win the lottery in the next month so i can hire a persoanl assistant who CARES to help me slowly get back up. No-one here now to encourage me or help with things that should be easy like ADLS and look after admin of running a small home let alone the physical tasks. I would so love to be just able to concentrate on ADLS, sel-care and work on psychology I've never had time to do all these years but have the resources. And to find an EXPERT and CARING mental health professional to work with me. Oh well. Need the lottery win first. Until then, I'm so nauseous with no food or water today, going to drag myself out of bed to the uncomfortable lounge at 3.30pm and turn tv on hoping to escape. At least 1 thing i have to be thankful for, i have govt funded frozen meals on freezer (albeit not nutricious or tasty) or otherwise i WOULD starve. I have to ask the universe WHY ME when my whole life was devoted to helping others? Am i REALLY that bad I have to end this way before next birthday in a few months??
What i wouldn't give for it to be now 7am and was getting up for luxury of hot shower and wash hair (the latter is necessary as I've developed a stress related rash on my face that needs medicated shampoo to help. Yep. I also look hideous and can't help myself 😢
Well explained. Reassuring. Thank you
I was stuck to the couch. No motivation. Couldn't force myself to do anything. I thought I was depressed. Meds didn't work. I tried everything. Finally, after years of this, a genius doctor suggested that I get my ears checked. Turns out I have an inner ear problem that affects balance, etc, and makes me feel a bit sick whenever I move my head. Apparently I have had it a very long time. If the meds don't work be sure to get checked out people!
Well. This explained nothing. Thanks
Cirs creates inflamation based depression.
Can be very strong and apparently unbased.
No antidepressant will help.
Reducing the ingfamation does.
Why am i still getting lot symptoms on meds??
I have Essential Head Tremors which is brain defect from unknown sources. At the same time I have depression and anxiety due to financial problems.
Now, my neurologist and movement disorder doctor prescribed me to take benzodiazepine to lessen my head tremors which is aggravated by my stresses. The meds do make me calmer and focus clearer but at the same time it stops my head from shaking.
However, this meds are to be taken as needed only and with my decision.
With that I practice meditation, breathing and acceptance and committment tools and self-compassion and good nutrition and sleep to help me decide rationally.
Its a lot of work, but I wouldn't want to get dependent on xanax.
The meds are only a crutch, but the internal healing process is key.
I'm on a benzo for over 20 yrs. It helps me
I now do a lot of exercise everyday,run for 10km(speed is about 6min40s/km) and do HIIT for about 1 hour(include using dumbbell, and I do “killer workouts”,very high intensity),I feel a lot better compared to my previous life. But I also do some other things,for example,yoga,not to overload myself,etc
Interesting information!
J’ai 32 ans et en 2019 Pendant mon premier épisode dépressif J’ai pris zoloft anafranil seroplex et deroxat sans succès avec des effet indésirable comme problème d’erection nausée anxiété décuplé. J’ai arrêté les traitements au bout de 6 mois et je m’en suis sorti avec le temps et la psychothérapie. Malheureusement cet été c’est revenu après que mon chien est fait des crises d’épilepsie je n’ai plus dormi et j’ai commencé à plus avoir goût à rien. J’ai aussi un tdah depuis l’enfance mais je refuse désormais les traitements car il aggrave mon cas et j’en ai peur. J’espère que je m’en sortirai
The DOD/VA has only provided one good provider in my 16 years and she was temporary 😢 they never asks these types of questions
God bless you for what u are doing,my symptoms are gradually going away the one am praying for God to heal now is my thoughts and nightmare every night disturbing my sleep, have stop taking medication since 3 yrs now bc they work for a while and make symptoms worse
100% agree! Thank you dr Marks !
Thank you dr Tracy
I am ADHD/bipolar and epileptic. I have been off all medication’s, except my thyroid medication for about six years. Nothing I took worked the ADHD medicines. I took gave me seizures the seizure medicines. I took also gave me seizures as that is one of the side effects of every single seizure medicine they make.
The only thing that’s worked for me is a lot of meditation, CBD, eating cleanly getting enough rest and exercise. I live alone in the country with my dogs and cat and house rabbit and have carved out a nice little life for myself. I am not a fan of pharmaceuticals and believe me, I have tried many.
Love your Youtube page Dr. Marks! Very informative
Thank God for insta cart.
My two cents on Depression and Anxiety: first, I am a loving husband of over 35 yrs dealing with a spouse whom has suffered from Depression/Anxiety/Bi-polar for at least 33 years. it turns out her first symptoms started in the 3rd grade! I have been supportive and understanding listening and acting on the advice of dozens of medical professionals and Many psychiatrist through the decades. It was not until last year I realized any past treatments were just not producing positive results. Hundreds of medications later, glaucoma and hair loss, we decided to take a different path. I am NOT a medical professional so please do not take this as medical advice. We believe wholeheartedly that Depression/anxiety/bi-polar is NOT a disease but a "symptom" of something else. The drugs only treat the symptoms with massive side effects. 1. We are now under the care of a Doctor of Neuropathic Medicine NDM. 2. Detailed Blood work and detailed blood Allergy testing revealed stomach leakage as a result of a severe Wheat/Soy/Cabbage/basal allergy. 3 Her body was riddled with Yeast/Epstein Barr resulting in massive hormone imbalances and some brain swelling. Also her vitamins and mineral levels were totally off the charts "screwed up" 4. We are currently on a strict diet and supplements to restore her stomach microbiome and repair her leaky gut. 5. After just one month her taste buds began working, she can taste lemon for the first time in years, her mood is rock solid and stable, she is sleeping through the night, Constipation is completely gone. We will continue the treatment with hopes and prayers that her Glaucoma and hair loss will improve. Her DMD said he has successfully treated her type of glaucoma with diet. Patients have recovered much of their lost sight. Summary: Don't listen to MOST doctors (the ones that are not experienced in diet/stomach health) and especially psychiatrist (the ones that just push toxic pills that never order blood work). Demand they do they homework and perform MRI's/CT's on organs such as thyroid, pancreas, pituitary, Blood work, Allergy testing etc. It could be a tiny tumor or an allergy. Brain health begins and ends with diet and a healthy gut. If you are prediabetic or even worse diabetic threat that Immediately. Closing: we still have several years towards recovery but the bottom line is that she is recovering and on the correct path. In time we plan to reduce the number and quantity of medication but it will require constant effort. She has already been weened off of a highly addictive sleep narcotic after just a month. Prayers are greatly appreciated.
Anyone having issues driving due to ptsd 😢 what helped you 😢
whats your take on escitalopram? am taking them the last 2,5 years and the last 1,5 year am on only 5mg,but i feel great problem if i dont take them one day.
may god please help my beautiful handsome man his so kind and loveing and his sufffffering including MS. fukkk this world please help him god with helping him self.. love him so.
I love your YouTube page. I have had so many issues with ptsd after fracturing my leg. Having to stay in bed for months. I did have anxiety prior to that and depression I am on Zoloft. The Dr. raised my dosage it dosnt seem to help.
Thank you for bringing up the difficulty of self-care. It really, really can be almost painful–which most people cannot understand. My mom and I both have MDD, but I've been doing better than her. So I had to ask her every day, a few times a day (!) if she brushed her teeth. I sometimes hated myself for it. I felt so guilty, yet I'd insist softly, "Have you done it? Please do it. It's not important for today, but it's for the future–we don't want you to end up at a dentist. Please…" I cannot imagine what people who live alone feel, having no one to support them in this routine.
My Mom is doing so much better now. What's interesting, is that in the worst times (when she couldn't brush her teeth) she was still able to get out of bed Only to feed our cats and to clean after them. She knew I'd taken a good care of them but she wanted to be involved, as it was easier than to take a shower. Their love and affection is priceless. Having a fluffy member in the family helps immensely.
Doctor I need your help how can I get in touch