Parkinson’s Disease part I/ #dopamine#cell#damage/Dr. Florenal Joseph
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I am Dr. Marie Beatrice Hyppolite. I hold a doctorate in Health Science with an emphasis on Global Health and a master’s degree in social work. I have over 14 years of experience in the field of health and human services.
This podcast is primarily focused on mental health and the quality-of-life elements that affect it such as divorce, death, domestic violence, trauma, toxic relationships, and single parenthood to name a few. It is no secret that mental health challenges continue to profoundly impact modern society although not enough discussion is given due to stigma. Research has shown an increase of 25 % in mental health crises after COVID-19. It is important to have honest, uncomfortable conversations about mental health while being supportive. Although we are interdependent, change begins with the individual, hence “your world.”
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Dopamine is the messenger that connects your brain to your body—and in Parkinson's disease, this crucial connection slowly disappears. Dr. Floronal Joseph returns to unpack the devastating progression of this neurodegenerative condition affecting nearly 12 million people worldwide.
Most of us recognize the tremors, but Parkinson's brings a cascade of both physical and psychological challenges. When cells in the substantia nigra region of the brain degenerate and die, they can never repair or regenerate. The resulting dopamine shortage triggers not just the familiar shaking hands, but also bradykinesia (slowed movements), involuntary actions like excessive salivation, and the often-overlooked burden of depression and social isolation.
What makes Parkinson's particularly troubling is its wide reach. While prevalence increases with age, symptoms can appear as early as 12 years old. Men face approximately 1.5 times higher risk than women until age 85, creating unique challenges for male patients who may struggle more with visible symptoms that affect traditional notions of masculinity and independence. Dr. Joseph explains how this contrasts with Alzheimer's higher prevalence in women, offering fascinating insights into gender differences in neurological disease.
We also explore the surprising geographic patterns of Parkinson's, with higher rates in America's "Parkinson's belt" across Utah and Colorado, and industrial Midwest regions where environmental toxins create heightened risk. Even diet plays a significant role, with fiber intake affecting constipation—a common but frequently overlooked symptom.
With projections showing Parkinson's cases doubling to 25 million globally by 2050, understanding this complex condition has never been more urgent. Listen now to learn how medical science is working to identify causes and potential treatments for this devastating disease.