By Capital Blue Cross

For years, mental health has been discussed primarily in terms of emotions, behavior, and cognitive well-being. But emerging evidence shows it plays a far greater role in overall health than many realize – including a direct connection to heart disease.

According to the Centers for Disease Control and Prevention (CDC), mental health disorders can contribute to physical changes in the body that increase the risk of cardiovascular disease. These effects can arise from both short‑term episodes and long‑term conditions, influencing how the heart functions and how the body responds to stress.

“We often separate mental and physical health in conversation, but the body doesn’t make that distinction,” said Dr. Bernard DiCasimirro, Lead Medical Director for Behavioral Health at Capital Blue Cross. “Stress, anxiety, and depression can create real physiological changes that strain the heart. When we address mental wellness early, we’re also protecting long‑term heart health.”

Medical experts say the relationship is striking. According to the CDC, certain mental health disorders can elevate heart rate and blood pressure, restrict blood flow to the heart, and increase production of cortisol – the hormone responsible for the body’s “built‑in alarm system.”

Over time, these changes may contribute to calcium buildup in the arteries, metabolic disease, and other factors that raise the likelihood of heart problems.

Conditions such as chronic stress, depression, and post‑traumatic stress disorder (PTSD) have all been associated with higher cardiovascular risk.

Groups that face higher risks

Some populations are disproportionately affected due to existing mental health challenges or social stressors:

Couples in which one or both partners have PTSD, who may experience more conflict, elevated heart rate, or chronic high blood pressure.Veterans, who have higher rates of PTSD and related health complications.Women, especially those affected by PTSD or depression, who face an increased risk of heart disease.Racial and ethnic minority groups, who often experience health disparities, discrimination, and systemic barriers that contribute to higher blood pressure, increased heart rate, and poorer cardiovascular outcomes.Lifestyle factors impact the problem

Mental health disorders may also influence behaviors that increase cardiovascular risk, according to the CDC. People struggling with these conditions may become inactive, use tobacco, or take medications that inadvertently affect heart health. Some treatments have been linked to obesity, diabetes, atrial fibrillation, stroke, and even early death.

The connection goes both ways

Heart disease can also increase the risk of developing mental health disorders, said the American Heart Association. After experiencing a heart attack, stroke, or heart failure, many individuals report depression, anxiety, or heightened stress — often driven by pain, fear of disability, or financial hardship.

Taking action matters

Health professionals emphasize that recognizing and treating mental health issues, especially in the early stages, can lead to better outcomes for both the mind and body. Exercise, healthy eating, and quitting tobacco use remain key strategies for reducing heart disease risk and supporting emotional well-being.

Many health plans include access to behavioral health services, ranging from online therapy to care management support. Capital Blue Cross members can learn more by contacting Member Services at the number listed on their ID card.

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