CDC. Symptoms of depression among adults: United States. 2020. CDC Data Briefs – Number 379. https://www.cdc.gov/nchs/products/databriefs/db379.htm

Friedrich MJ. Depression is the leading cause of disability around the world. JAMA. 2017;317:1517.

PubMed 

Google Scholar
 

Greenberg P, Chitnis A, Louie D, Suthoff E, Chen SY, Maitland J, et al. The economic burden of adults with major depressive disorder in the United States (2019). Adv. Ther. 2023;40:4460–79.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Sarris J, O’Neil A, Coulson CE, Schweitzer I, Berk M. Lifestyle medicine for depression. BMC Psychiatry. 2014;14:107. https://doi.org/10.1186/1471-244X-14-107

Article 
PubMed 
PubMed Central 

Google Scholar
 

Opie RS, O’Neil A, Itsiopoulos C, Jacka FN. The impact of whole-of-diet interventions on depression and anxiety: a systematic review of randomised controlled trials. Public Health Nutr. 2015;18:2074–93.

Article 
PubMed 

Google Scholar
 

Opie RS, O’Neil A, Jacka FN, Pizzinga J, Itsiopoulos C. A modified mediterranean dietary intervention for adults with major depression: dietary protocol and feasibility data from the SMILES trial. Nutr. Neurosci. 2018;21:487–501.

Article 
PubMed 

Google Scholar
 

Hearing CM, Chang WC, Szuhany KL, Deckersbach T, Nierenberg AA, Sylvia LG. Physical exercise for treatment of mood disorders: a critical review. Curr. Behav. Neurosci. Rep. 2016;3:350–9.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Taylor CT, Stein MB, Simmons AN, He F, Oveis C, Shakya HB, et al. Amplification of positivity treatment for anxiety and depression: a randomized experimental therapeutics trial targeting social reward sensitivity to enhance social connectedness. Biol. Psychiatry. 2024;95:434–43.

Article 
PubMed 

Google Scholar
 

Farah WH, Alsawas M, Mainou M, Alahdab F, Farah MH, Ahmed AT, et al. Non-pharmacological treatment of depression: a systematic review and evidence map. Evidence Based Medicine. 2016;21:214–21.

Article 
PubMed 

Google Scholar
 

Hofmann SG, Gómez AF. Mindfulness-based interventions for anxiety and depression. Psychiatric Clinics of North America. 2017;40:739–49.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Noetel M, Sanders T, Gallardo-Gómez D, Taylor P, Del Pozo Cruz B, van den Hoek D, et al. Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials. BMJ. 2024;384:e075847. https://doi.org/10.1136/bmj-2023-075847

Article 
PubMed 
PubMed Central 

Google Scholar
 

Schuch F, Vancampfort D, Firth J, Rosenbaum S, Ward P, Reichert T, et al. Physical activity and sedentary behavior in people with major depressive disorder: a systematic review and meta-analysis. J. Affect. Disord. 2017;210:139–50.

Article 
PubMed 

Google Scholar
 

Parletta N, Zarnowiecki D, Cho J, Wilson A, Bogomolova S, Villani A, et al. A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: a randomized controlled trial (HELFIMED). Nutr. Neurosci. 2019;22:474–87.

Article 
CAS 
PubMed 

Google Scholar
 

Francis HM, Stevenson RJ, Chambers JR, Gupta D, Newey B, Lim CK. A brief diet intervention can reduce symptoms of depression in young adults – a randomised controlled trial. PLoS One. 2019;14:e0222768.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Carney CE, Edinger JD, Kuchibhatla M, Lachowski AM, Bogouslavsky O, Krystal AD, et al. Cognitive behavioral insomnia therapy for those with insomnia and depression: a randomized controlled clinical trial. Sleep. 2017;40:zsx019.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Hertenstein E, Trinca E, Wunderlin M, Schneider CL, Züst MA, Fehér KD, et al. Cognitive behavioral therapy for insomnia in patients with mental disorders and comorbid insomnia: a systematic review and meta-analysis. Sleep Med. Rev. 2022;62:101597.

Article 
PubMed 

Google Scholar
 

Shah RV, Grennan G, Zafar-Khan M, Alim F, Dey S, Ramanathan D, et al. Personalized machine learning of depressed mood using wearables. Transl. Psychiatry. 2021;11:338.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Nan J, Herbert MS, Purpura S, Henneken AN, Ramanathan D, Mishra J. Personalized machine learning-based prediction of wellbeing and empathy in healthcare professionals. Sensors. 2024;24:2640.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Wittenborn AK, Hosseinichimeh N. Exploring personalized psychotherapy for depression: a system dynamics approach. PLoS One. 2022;17:e0276441.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Xiao S, Gaier ED, Mazow ML, Stout AU, Travers DA, Angjeli E, et al. Improved adherence and treatment outcomes with an engaging, personalized digital therapeutic in amblyopia. Sci. Rep. 2020;10:8328.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Kulzer B, Daenschel W, Daenschel I, Schramm W, Messinger D, Weissmann J, et al. Integrated personalized diabetes management improves glycemic control in patients with insulin-treated type 2 diabetes: results of the PDM-ProValue study program. Diabetes Res. Clin. Pract. 2018;144:200–12.

Article 
PubMed 

Google Scholar
 

Linn AJ, van Dijk L, van Weert J, Gebeyehu BG, van Bodegraven AA, Smit EG. Creating a synergy effect: a cluster randomized controlled trial testing the effect of a tailored multimedia intervention on patient outcomes. Patient Educ. Couns. 2018;101:1419–26.

Article 
PubMed 

Google Scholar
 

Chiang P-H, Wong M, Dey S. Using wearables and machine learning to enable personalized lifestyle recommendations to improve blood pressure. IEEE J. Transl. Eng. Health Med. 2021;9:1–13.

Article 

Google Scholar
 

van Bronswijk SC, DeRubeis RJ, Lemmens L, Peeters F, Keefe JR, Cohen ZD, et al. Precision medicine for long-term depression outcomes using the Personalized Advantage Index approach: cognitive therapy or interpersonal psychotherapy? Psychol. Med. 2021;51:279–89.

Article 
PubMed 

Google Scholar
 

Nye A, Delgadillo J, Barkham M. Efficacy of personalized psychological interventions: a systematic review and meta-analysis. J. Consult. Clin. Psychol. 2023;91:389–97.

Article 
PubMed 

Google Scholar
 

Chekroud AM, Hawrilenko M, Loho H, Bondar J, Gueorguieva R, Hasan A, et al. Illusory generalizability of clinical prediction models. Science (1979). 2024;383:164–7.

CAS 

Google Scholar
 

Chatterjee S, Mishra J, Sundram F, Roop P. Towards personalised mood prediction and explanation for depression from biophysical data. Sensors. 2023;24:164.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Thornicroft G, Ahuja S, Barber S, Chisholm D, Collins PY, Docrat S, et al. Integrated care for people with long-term mental and physical health conditions in low-income and middle-income countries. Lancet Psychiatry. 2019;6:174–86.

Article 
PubMed 

Google Scholar
 

Hodgkinson S, Godoy L, Beers LS, Lewin A. Improving mental health access for low-income children and families in the primary care setting. Pediatrics. 2017;139:e20151175.

Article 
PubMed 

Google Scholar
 

Rathod S, Pinninti N, Irfan M, Gorczynski P, Rathod P, Gega L, et al. Mental health service provision in low- and middle-income countries. Health Serv. Insights. 2017;10:1178632917694350.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Gotlib IH, Joormann J. Cognition and depression: current status and future directions. Annu. Rev. Clin. Psychol. 2010;6:285–312.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Atique-Ur-Rehman H, Neill JC. Cognitive dysfunction in major depression: From assessment to novel therapies. Pharmacol. Ther. 2019;202:53–71.

Article 
CAS 
PubMed 

Google Scholar
 

Chakrabarty T, Hadjipavlou G, Lam RW. Cognitive dysfunction in major depressive disorder: assessment, impact, and management. Focus (Am. Psychiatr. Publ). 2016;14:194–206.

PubMed 
PubMed Central 

Google Scholar
 

Remes O, Mendes JF, Templeton P. Biological, psychological, and social determinants of depression: a review of recent literature. Brain Sci. 2021;11:1633.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Perini G, Cotta Ramusino M, Sinforiani E, Bernini S, Petrachi R, Costa A. Cognitive impairment in depression: recent advances and novel treatments. Neuropsychiatr. Dis. Treat. 2019;15:1249–58.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Sekhon, S & Marwaha, R. Depressive cognitive disorders. 2025.

Culpepper L, Lam RW, McIntyre RS. Cognitive impairment in patients with depression: awareness, assessment, and management. J. Clin. Psychiatry. 2017;78:1383–94.

Article 
PubMed 

Google Scholar
 

Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J. Gen. Intern. Med. 2001;16:606–13.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

First, M, Williams, JB, Spitzer, R & Gibbon, M SCID – structured clinical interview for DSM-IV axis I disorders. 2002. https://eprovide.mapi-trust.org/instruments/structured-clinical-interview-for-dsm-iv-axis-i-disorders

Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, et al. The montreal cognitive assessment, MoCA: a brief screening tool for mild cognitive impairment. J. Am. Geriatr. Soc. 2005;53:695–9.

Article 
PubMed 

Google Scholar
 

Faul F, Erdfelder E, Buchner A, Lang A-G. Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. Behav. Res. Methods. 2009;41:1149–60.

Article 
PubMed 

Google Scholar
 

ClinicalTrials.gov NCT05662254. UCSD Depression Trial → PERsonalized Mood Augmentation Trial for Depressed Mood. https://clinicaltrials.ucsd.edu/trial/NCT05662254.

Misra A, Ojeda A, Mishra J. BrainE: a digital platform for evaluating, engaging and enhancing brain function. 2018. Regents of the University of California Copyright SD2018-816. https://play.google.com/store/apps/details?id=com.neatlabs.braine&hl=en_US.

Merikangas KR, Swendsen J, Hickie IB, Cui L, Shou H, Merikangas AK, et al. Real-time mobile monitoring of the dynamic associations among motor activity, energy, mood, and sleep in adults with bipolar disorder. JAMA Psychiatry. 2019;76:190–8.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Spitzer RL, Kroenke K, Williams JBW, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch. Intern. Med. 2006;166:1092–7.

Article 
PubMed 

Google Scholar
 

Kessler RC, Sampson NA, Berglund P, Gruber MJ, Al-Hamzawi A, Andrade L, et al. Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys. Epidemiol. Psychiatr. Sci. 2015;24:210–26.

Article 
CAS 
PubMed 

Google Scholar
 

Kalin NH. The critical relationship between anxiety and depression. American Journal of Psychiatry. 2020;177:365–7.

Article 
PubMed 

Google Scholar
 

Hamilton M. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry. 1960;23:56–62.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Turner-Bowker D, Hogue SJ. Short form 12 health survey (SF-12). in Encyclopedia of quality of life and well-being research. Springer Netherlands, Dordrecht, 2014. pp. 5954-7. https://doi.org/10.1007/978-94-007-0753-5_2698

Brown KW, Ryan RM. The benefits of being present: mindfulness and its role in psychological well-being. J. Pers. Soc. Psychol. 2003;84:822–48.

Article 
PubMed 

Google Scholar
 

Gawande R, To MN, Pine E, Griswold T, Creedon TB, Brunel A, et al. Mindfulness training enhances self-regulation and facilitates health behavior change for primary care patients: a randomized controlled trial. J. Gen. Intern. Med. 2019;34:293–302.

Article 
PubMed 

Google Scholar
 

Schuman-Olivier Z, Trombka M, Lovas DA, Brewer JA, Vago DR, Gawande R, et al. Mindfulness and behavior change. Harv. Rev. Psychiatry. 2020;28:371–94.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Oquendo MA, Halberstam B, Mann J. Risk factors for suicidal behavior. The utility and limitations of research instruments. Standardized Evaluation in Clinical Practice. Review of Psychiatry. 2003;8:103–30.


Google Scholar
 

Balasubramani PP, Ojeda A, Grennan G, Maric V, Le H, Alim F, et al. Mapping cognitive brain functions at scale. Neuroimage. 2021;231:117641.

Article 
PubMed 

Google Scholar
 

Nan J, Grennan G, Ravichandran S, Ramanathan D, Mishra J. Neural activity during inhibitory control predicts suicidal ideation with machine learning. NPP—Digital Psychiatry and Neuroscience. 2024;2:10.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Grennan GK, Ramanathan DS, Mishra J, Withers MC. Differences in interference processing and frontal brain function with climate trauma from California’s deadliest wildfire. PLOS Climate. 2023;2:e0000125.

Article 

Google Scholar
 

Mo Z, Grennan G, Kulkarni A, Ramanathan D, Balasubramani PP, Mishra J. Parietal alpha underlies slower cognitive responses during interference processing in adolescents. Behav Brain Res. 2023;443:114356.

Article 
PubMed 

Google Scholar
 

Ramanathan D, Nan J, Grennan G, Jaiswal S, Purpura S, Manchanda J, et al. Modulation of posterior default mode network activity during interoceptive attention and relation to mindfulness. Biological Psychiatry Global Open Science. 2024;4:100384.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Grennan G, Balasubramani PP, Alim F, Zafar-Khan M, Lee EE, Jeste DV, et al. Cognitive and neural correlates of loneliness and wisdom during emotional bias. Cerebral Cortex. 2021;31:3311–22.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Kato R, Balasubramani PP, Ramanathan D, Mishra J. Utility of cognitive neural features for predicting mental health behaviors. Sensors. 2022;22:3116.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Grennan G, Balasubramani PP, Vahidi N, Ramanathan D, Jeste DV, Mishra J. Dissociable neural mechanisms of cognition and well-being in youth versus healthy aging. Psychol. Aging. 2022;37:827–42.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Balasubramani PP, Walke A, Grennan G, Perley A, Purpura S, Ramanathan D, et al. Simultaneous gut-brain electrophysiology shows cognition and satiety specific coupling. Sensors. 2022;22:9242.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Fakhraei L. Mapping large-scale networks associated with action, behavioral inhibition and impulsivity. eNeuro. 2021;8:ENEURO.0406-20.2021.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Fakhraei L, Francoeur M, Balasubramani PP, Tang T, Hulyalkar S, Buscher N, et al. Electrophysiological correlates of rodent default-mode network suppression revealed by large-scale local field potential recordings. Cereb. Cortex Commun. 2021;2:034.


Google Scholar
 

Jaiswal S, Nan J, Dizon S, Young JO, Purpura SR, Manchanda JK, et al. Breath-focused mindfulness and compassion training in parent-child dyads: Pilot Intervention Study. JMIR Form. Res. 2025;9:e69607.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Jaiswal S, Purpura SR, Manchanda JK, Nan J, Azeez N, Ramanathan D, et al. Design and Implementation of a brief digital mindfulness and compassion training app for health care professionals: cluster randomized controlled trial. JMIR Ment. Health. 2024;11:e49467.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Molnar C. 5.9 shapley values | interpretable machine learning. in Interpretable Machine Learning. 2020.

Asarnow LD, Manber R. Cognitive behavioral therapy for insomnia in depression. Sleep Med. Clin. 2019;14:177–84.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Sallis R. Exercise is medicine: a call to action for physicians to assess and prescribe exercise. Phys. Sportsmed. 2015;43:22–6.

Article 
PubMed 

Google Scholar
 

Taylor CT, Lyubomirsky S, Stein MB. Upregulating the positive affect system in anxiety and depression: outcomes of a positive activity intervention. Depress. Anxiety. 2017;34:267–80.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Cohen J. Statistical power analysis for the behavioral sciences. Routledge; 2013. https://doi.org/10.4324/9780203771587.

Lane K. What Is Robust Regression and How Do You Do It? (2002).

Google. Gemini developer API. 2024. https://ai.google.dev/gemini-api/docs

Heinz MV, Mackin DM, Trudeau BM, Bhattacharya S, Wang Y, Banta HA, et al. Randomized trial of a generative AI chatbot for mental health treatment. NEJM AI 2025;2. https://doi.org/10.1056/AIoa2400802

Siddals S, Torous J, Coxon A. ‘It happened to be the perfect thing’: experiences of generative AI chatbots for mental health. Npj mental health research. 2024;3:48.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Farzan M, Ebrahimi H, Pourali M, Sabeti F. Artificial intelligence-powered cognitive behavioral therapy chatbots, a systematic review. Iran. J. Psychiatry. 2025;20:102–10.

PubMed 
PubMed Central 

Google Scholar
 

Yonatan‐Leus R, Brukner H. Comparing perceived empathy and intervention strategies of an AI chatbot and human psychotherapists in online mental health support. Couns. Psychother. Res. 2025;25. https://doi.org/10.1002/capr.12832

Spytska L. The use of artificial intelligence in psychotherapy: development of intelligent therapeutic systems. BMC Psychol. 2025;13:175.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Khawaja Z, Bélisle-Pipon J-C. Your robot therapist is not your therapist: understanding the role of AI-powered mental health chatbots. Front. Digit. Health. 2023;5:1278186.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Papakostas GI, Petersen T, Mahal Y, Mischoulon D, Nierenberg AA, Fava M. Quality of life assessments in major depressive disorder: a review of the literature. Gen. Hosp. Psychiatry. 2004;26:13–17.

Article 
PubMed 

Google Scholar
 

Nicolucci A, Haxhi J, D’Errico V, Sacchetti M, Orlando G, Cardelli P, et al. Effect of a behavioural intervention for adoption and maintenance of a physically active lifestyle on psychological well-being and quality of life in patients with type 2 diabetes: the IDES_2 randomized clinical trial. Sports Medicine. 2022;52:643–54.

Article 
PubMed 

Google Scholar
 

Scott AJ, Webb TL, Martyn-St James M, Rowse G, Weich S. Improving sleep quality leads to better mental health: a meta-analysis of randomised controlled trials. Sleep Med. Rev. 2021;60:101556.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Vittengl JR, Jha MK, Minhajuddin A, Thase ME, Jarrett RB. Quality of life after response to acute-phase cognitive therapy for recurrent depression. J. Affect. Disord. 2021;278:218–25.

Article 
CAS 
PubMed 

Google Scholar
 

Liu L, Wang K, Xu D, Wang Y, Xu X, Wang Q, et al. Effectiveness of cognitive rehabilitation in improving symptoms and restoring cognitive functions in patients with depression: an updated meta-analysis of randomized controlled trials. Alpha psychiatry. 2024;25:727–36.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Ngandu T, Lehtisalo J, Korkki S, Solomon A, Coley N, Antikainen R, et al. The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER). Alzheimer’s & Dementia. 2022;18:1325–34.

Article 

Google Scholar
 

Balsamo F, Berretta E, Meneo D, Baglioni C, Gelfo F. The complex relationship between sleep and cognitive reserve: a narrative review based on human studies. Brain Sci. 2024;14:654.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, et al. Dementia prevention, intervention, and care: 2020 report of the lancet commission. Lancet. 2020;396:413–46.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Zou C, Amos-Richards D, Jagannathan R, Kulshreshtha A. Effect of home-based lifestyle interventions on cognition in older adults with mild cognitive impairment: a systematic review. BMC Geriatr. 2024;24:200.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Naaman RK, Alashmali S, Bakhsh MA, Alneami SA, Algamdi ES, Al-Ghamdi GA, et al. Association between healthy lifestyle and cognitive function in middle-aged and older adults. Healthcare. 2025;13:1140.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Vidyanti AN, Rahmawati F, Rahman RH, Prodjohardjono A, Gofir A. Lifestyle interventions for dementia risk reduction: A review on the role of physical activity and diet in Western and Asian Countries. J. Prev. Alzheimers Dis. 2025;12:100028.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Ding Z, Leung P-Y, Lee T, Chan AS. Effectiveness of lifestyle medicine on cognitive functions in mild cognitive impairments and dementia: a systematic review on randomized controlled trials. Ageing Res. Rev. 2023;86:101886.

Article 
PubMed 

Google Scholar
 

Baker LD, Espeland MA, Whitmer RA, Snyder HM, Leng X, Lovato L, et al. Structured vs self-guided multidomain lifestyle interventions for global cognitive function. JAMA. 2025;334:681–91.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Keller AS, Leikauf JE, Holt-Gosselin B, Staveland BR, Williams LM. Paying attention to attention in depression. Transl. Psychiatry. 2019;9:279.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Nikolin S, Tan YY, Schwaab A, Moffa A, Loo CK, Martin D. An investigation of working memory deficits in depression using the n-back task: a systematic review and meta-analysis. J. Affect. Disord. 2021;284:1–8.

Article 
PubMed 

Google Scholar
 

Fales CL, Barch DM, Rundle MM, Mintun MA, Snyder AZ, Cohen JD, et al. Altered emotional interference processing in affective and cognitive-control brain circuitry in major depression. Biol. Psychiatry. 2008;63:377–84.

Article 
PubMed 

Google Scholar
 

Kaiser RH, Andrews-Hanna JR, Spielberg JM, Warren SL, Sutton BP, Miller GA, et al. Distracted and down: neural mechanisms of affective interference in subclinical depression. Soc. Cogn. Affect. Neurosci. 2015;10:654–63.

Article 
PubMed 

Google Scholar
 

Sharma PK, Kumra R. Relationship between mindfulness, depression, anxiety and stress: mediating role of self-efficacy. Pers. Individ. Dif. 2022;186:111363.

Article 

Google Scholar
 

Martínez-Pérez I, García-Rodríguez A, Morales-Rodríguez FM, Pérez-Mármol JM. Mindfulness abilities are associated with anxiety levels, emotional intelligence, and perceived self-efficacy. Sustainability. 2023;15:4729.

Article 

Google Scholar
 

Moradi F, Heshmati J, Daneshzad E, Ahmadi A, Jafari T, Persad E, et al. Association between dietary satisfaction and depression, anxiety and stress in obese and overweight patients during the coronavirus pandemic. Clin. Nutr. ESPEN. 2021;45:399–403.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Craft LL, Perna FM. The benefits of exercise for the clinically depressed. Prim. Care Companion CNS Disord. 2004;6:104–11.


Google Scholar
 

Fernández‐López R, Riquelme‐Gallego B, Bueno‐Cavanillas A, Khan KS. Influence of placebo effect in mental disorders research: a systematic review and meta‐analysis. Eur. J. Clin. Invest. 2022;52:13762.

Article 

Google Scholar
 

Lindheimer JB, O’Connor PJ, Dishman RK. Quantifying the placebo effect in psychological outcomes of exercise training: a meta-analysis of randomized trials. Sports Medicine. 2015;45:693–711.

Article 
PubMed 

Google Scholar
 

Cuijpers P, Miguel C, Harrer M, Plessen CY, Ciharova M, Ebert D, et al. Cognitive behavior therapy vs. control conditions, other psychotherapies, pharmacotherapies and combined treatment for depression: a comprehensive meta‐analysis including 409 trials with 52,702 patients. World Psychiatry. 2023;22:105–15.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Leitner J, Chiang P-H, Agnihotri P, Dey S. The effect of an AI-based, autonomous, digital health intervention using precise lifestyle guidance on blood pressure in adults with hypertension: single-arm nonrandomized trial. JMIR Cardio. 2024;8:e51916.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Tang Y, Gierc M, La H, Liu S, Lam RW, Puterman E, et al. Feasibility and preliminary effects of an app-based physical activity intervention for individuals with depression (MoodMover): a protocol for a single-arm, pre-post intervention study. PLoS One. 2025;20:e0321958.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Billingham SAM, Whitehead AL, Julious SA. An audit of sample sizes for pilot and feasibility trials being undertaken in the United Kingdom registered in the United Kingdom Clinical Research Network database. BMC Med. Res. Methodol. 2013;13:104.

Article 
PubMed 
PubMed Central 

Google Scholar
 

Braund TA, Tillman G, Palmer DM, Gordon E, Rush AJ, Harris A. Antidepressant side effects and their impact on treatment outcome in people with major depressive disorder: an iSPOT-D report. Transl. Psychiatry. 2021;11:417.

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Share.

Comments are closed.